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248 In smokers, whom have been proven in multiple studies to have low blood levels of vitamin C, oral supplementation with 2 grams vitamin C per day has been shown to significantly decrease urinary isoprostanes, 249 markers of oxidative stress, and monocyte adhesion to the endothelial lining of blood vessels, one of the early stages in the development of dangerous atherosclerotic plaque

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doi: 10.3389/fnut.2023.1015046 Received 09 August 2022 Accepted 16 February 2023 Published 06 March 2023 Volume 10 - 2023 Edited by Domenico Sergi, University of Ferrara, Italy Reviewed by Tianlin Gao, Qingdao University, China

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