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Furthermore, probiotic interventions appear to ameliorate inflammatory biomarkers (e.g., C-reactive protein), enhance glycemic control, and improve insulin metabolism in patients with type 2 diabetes or metabolic syndrome (425429), as well as in pregnant women diagnosed with gestational diabetes mellitus (425, 426)

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However, it has not been applied in a clinical setting and its underlying molecular mechanisms require further investigation

Basal OCR was measured using the Seahorse XF24 Flux analyzer, as previously described 9

As DNA methylation appears to be an integral component of the pathogenesis of endometriosis, the identification of DNA methylation biomarkers would likely help better understand its causes and aggravating factors as well as potentially facilitate its diagnosis and support the development of new therapeutic approaches