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Following neuronal damage, tau is released into extracellular space and may be increased in the CSF

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In the context of osteoporosis, tocotrienols therapy has provided significant beneficial outcomes

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178 Nuclear localization of NFATC1 is promoted by increased intracellular Ca 2+ levels in response to activation of co-stimulatory receptors, which together with RANKL signaling is required for osteoclastogenesis