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Mateuszuk L, Jasztal A, Maslak E, Gasior-Glogowska M, Baranska M, Sitek B, Kostogrys R, Zakrzewska A, Kij A, Walczak M, Chlopicki S (2016) Antiatherosclerotic effects of 1-methylnicotinamide in apolipoprotein E/low-density lipoprotein receptor-deficient mice: a comparison with nicotinic acid

The apparent permeability coefficient for DSIP penetration of BMEC monolayers was in a range similar to water-soluble substances (e.g

doi: 10.3390/molecules25225474 61 CavakNGumustasMKCekicSD

Johnston, O., Rose, C

Safety can also depend on the intended purpose

Furthermore, we examine the challenges in translating these findings into clinical practice, including issues with bloodbrain barrier penetration and the need for precise receptor targeting