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The three-dimensional structure of peptide-MHC complexes

Four years later, clinical trial results showed that FixVac, based on RNALPX, achieved remarkable outcomes in combination with immune checkpoint blocking therapy, demonstrating its effectiveness as a melanoma immunotherapy [28]

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Moreover, various tumor suppressors, such as p53 and BRCA1-associated protein 1 (BAP1), have been discovered to deter cancer progression by obstructing ferroptosis [9]

Through suitable modifications in surface properties these NPs can also release an active ingredient in a controlled manner at the target site