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In vivo studies demonstrated that the MnG combined with anti-PD-L1 (PD-L1) therapy significantly enhanced dendritic cell maturation in lymph nodes and cytotoxic T lymphocyte infiltration, compared to PD-L1 treatment alone

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They are important in the processes of oncogenesis, cancer progression, drug resistance, as well as the metabolism and biosynthesis of prostaglandins, leukotrienes and steroids [17]

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