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Males affected with 5-reductase-2 deficiency have non-palpable prostates on rectal exam, prostates that are 1/10 the volume of normal males on MRI (1, 6, 46)

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This binding sequesters the peptide, protecting it from rapid enzymatic degradation and renal clearance, thereby extending its plasma half-life to several days

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Cold storage slows the natural degradation process that begins as soon as the peptide is in liquid form, extending the window during which the solution remains suitable for research use