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In this study, scientists found that activation of cGAS-STING signaling increased the levels of mitochondrial reactive oxygen species, which induced the phosphorylation of mammalian sterile 20-like kinase 1 and then activated forkhead box1, subsequently promoting FLS migration and invasion (64)

doi:10.3390/ijms18010208

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Numerous studies have proposed that GHK-Cu acts as a potential SIRT1 activator, thereby highlighting its multifaceted role in cellular processes, especially its capacity to enhance SIRT1 activity ( in vivo and in vitro experiments