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Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma

CD14 + CD16 + monocytes are involved in daratumumab-mediated myeloma cells killing and in anti-CD47 therapeutic strategy

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Behere, Rishikesh V et al

A well-designed carrier system can shield B12 from degradation, facilitate its transport through the GI tract, control its release at the appropriate site in small intestine (the ileum), and promote efficient absorption