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If you demand randomized controlled trials for efficacy claims, you should demand epidemiological data for safety claims

In 1998 the cuprizone animal model experienced a comeback as the group of Matsushima (Hiremath et al., 1998) characterized cuprizone-induced de- and remyelination in the corpus callosum (CC) of C57BL/6 mice

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Steric hindrance is the major limiting factor in the synthesis of the B 12 coenzyme analogs