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Long-standing GERD with significant esophageal damage may require longer treatment periods and show slower response compared to milder, more recent-onset reflux

They require finding a physician who knows the current regulatory picture, uses compliant sourcing, and can make an informed evaluation of whether a specific compound is appropriate for a specific patient

Brubaker says drugs need to be carefully tested in stages before they are approved for use in people

The type and location of the tear will determine the severity of the injury and the treatment options available

OConnor CM, Perl A, Leonard D, Sangodkar J, Narla G