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Furthermore, methionine restriction has been found to reduce histone H3K4 methylation (H3K4me3) in the promoter region of key genes involved in Th17 cell proliferation and cytokine production, thereby reducing the proliferation and function of pathogenic Th17 cells [54]

10.1038/s41575-019-0157-3 101

Clinical trials including 219 participating IBD cases showed a difference between Caucasian and Asian races [133, 134]

The foremost prominent low relative molecular mass antioxidants in plants are water-soluble ascorbate (Asc), glutathione, and phenols, and liposoluble tocopherols, tocotrienols, and carotenoids (Figure 4)