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(1983) examined the biochemical alterations in liver and blood, and the histological findings in the liver of female C57BL/6J mice after a single oral administration of carbon tetrachloride in liquid paraffin at doses of 0.02, 0.5 or 1.5 ml/kg body weight (calculated to be 32, 797 or 2391 mg/kg body weight) at various times from 15 to 327 h after administration

doi: 10.1186/s42522-023-00079-0 21 AyobolaE

doi: 10.1186/s13075-022-02852-4 98 ZhangWDohertyMBardinTPascualEBarskovaVConaghanPet al

His-Tag Protease Contamination A non-obvious but well-documented mechanism

Since ML171 is structurally related to some commonly used phenothiazine-derived anti-psychotic drugs (e.g., chlorpromazine), it may interfere with receptors for serotonin and adrenaline (Diebold et al., 2015