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E., Yamada, K

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Natalie Rasgon, MD, PhD, professor of psychiatry and behavioral sciences at Stanford, described the findings as an exciting addition to our understanding of the mechanisms of depressive illness. As a clinical psychiatrist, I have treated many people with this disorder in my practice, she said

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Amifostine at a dose of 25 mg/kg significantly reduced oxaliplatin-induced c-Fos, nitrotyrosine, and activating transcription factor 3 (ATF3) expression, showing protective effects against nitrosative stress, neuronal hyperactivation and neuronal damage to dorsal root ganglion neurons in mice [147]