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CJC-1295 (No-DAC) enhances natural GH-releasing hormone signaling, while Ipamorelin acts as a selective ghrelin receptor agonist

Drug Test Anal 14, 1877-1890 (2022)

The Phase 3 trial reported no significant adverse effects on fasting glucose or HbA1c at 26 weeks (PMID 18057338)

doi: 10.1210/jc.2008-1357 Summary Keywords growth hormone, insulin-like growth factor-I, intra-portal insulin, acromegaly, adult growth hormone deficiency, hepatic growth hormone sensitivity Citation Yuen KCJ, Hjortebjerg R, Ganeshalingam AA, Clemmons DR and Frystyk J (2024) Growth hormone/insulin-like growth factor I axis in health and disease states: an update on the role of intra-portal insulin

Descriptive biopsy signals were strong

Product Information How it works It stimulates the growth hormone releasing hormone receptor and the ghrelin/growth hormone secretagogue receptor to promote the natural release of growth hormone