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This systemic approach differs fundamentally from pharmaceutical interventions that target single pathways

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For example, TLR signaling via MyD88-dependent pathways requires TNF receptor-associated factor 6 (TRAF6)

Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers

However, no abnormal behaviors are observed within their home environments or during behavioral tests, as indicated by consistent movement distances in the OFT