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From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models

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In particular, aerobic respiration by mitochondria (the powerhouses of the cell) leads to the production of ROS as oxygen is gradually converted into water

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10.1177/135245859700300205 68 FranklinR

Rather than guessing with individual ingredients, you get a research-backed combination designed to work across multiple energy pathways