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A plethysmometer (IITC Life Science, Woodland Hills, CA, USA) was used to quantify the edema volume by immersion of the mouse paw as described previously (Tarighi et al , 2019)

GH and IGF signaling in the kidney GH receptor The GHR is expressed in most tissues, including the kidney

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Sustained inflammation and oxidative stress can promote the activation and proliferation of HSCs, exacerbating the deposition of extracellular matrix and leading to the formation of fibrosis [224]

Cyanocobalamin stimulates blood formation, activates creatine synthesis, fat metabolism, and methionine biosynthesis, and normalizes the process of food assimilation

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