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The dose may be increased if the starting dose was well tolerated for the first three cycles

Additionally, dietary modifications like gluten-free or casein-free diets should be managed with support from healthcare providers or dietitians

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The answer, as with all things in research, is: it depends on the model and the objective

Among those who felt they needed to self-medicate, the main reasons given were to improve fatigue and to reduce brain fog and pins and needles