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The production of superoxide (O 2 ) is thought to occur at Complex I (NADH dehydrogenase), Complex II (succinate dehydrogenase), or Complex III (coenzyme Q-cytochrome c reductase), but under normal metabolic conditions, Complex III is thought to be the main sites of superoxide production

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Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress

The formation of ruby coloured dispersion was an indicator of nanoparticles formation[29]

Nature 560 , 360364 (2018)

It is noted that, in mammals without chronic diseases, such as HIV infection, diabetes, etc, which might impair physiologic GSH metabolism, a strategy for the pharmaceutical administration of other antioxidants which improve GSH metabolism or compounds which are themselves appropriate antioxidants may be employed