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Int J.Mol.Sci

The age pigment lipofuscin causes oxidative stress, lysosomal dysfunction, and pyroptotic cell death

In vivo experiments in which muscles of the rat were subjected to mechanical damage or injection of a myotoxic agent also demonstrated (Hill & Goldspink, 2003) that MGF precedes muscle satellite (stem) cell activation

Disease Mechanisms in ALS Whilst the proteins associated genetically or pathologically with ALS are diverse in function and structure, similar disease mechanisms are implicated