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362,363 When the concentration of NO exceeds 150 nm, the nitroso stress in the tumor microenvironment increases and the independent stress sensor is activated

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Another study reported that GABA production was induced locally in tobacco and soybean leaves when challenged with insect damage (Bown et al., 2002)

Acknowledgements This work was supported by Ministero dellIstruzione, dellUniversit e della Ricerca of Italy, Progetto PONRicerca e Competitivit 20072013PON01_01802: Sviluppo di molecole capaci di modulare vie metaboliche intracellulari redoxsensibili per la prevenzione e la cura di patologie infettive, tumorali, neurodegenerative e loro delivery mediante piattaforme nano tecnologiche, and PON01_02512: Ricerca e sviluppo di bioregolatori attivi sui meccanismi epigenetici dei processi infiammatori nelle malattie croniche e degenerative