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Shima Hadidchi offers a comprehensive, medically supervised approach that prioritizes patient safety and long-term success

ChengHQiuYXuYChenLMaKTaoMet al

Because the Fc domain is translated directly upstream of a peptide linker and N-terminus of the FGF21 variant, the N-terminus is protected from degradation by dipeptidyl peptidase (DPP) enzymes (296)

Methionine in the form of S-adenosylmethionine (SAM) is required for many methylation reactions, including DNA methylation

Additional information Peer review information Nature Communications thanks Fabian Filipp and William Gallagher and the other anonymous reviewer(s) for their contribution to the peer review of this work