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For instance, AZD1775 (adavosertib) monotherapy has demonstrated antitumor activity in treatment-refractory solid tumors with CCNE1 amplification, with particularly encouraging responses observed in epithelial ovarian cancer in a phase II trial 198 (NCT03253679, ClinicalTrials.gov, 2023)

An analysis of six clinical trials found that AOD 9604 had a safety profile comparable to placebo and did not act through the IGF-1 pathway

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Epitalon Research# Epitalon research is primarily from one research group: Key studies : Khavinson et al

T H 2-type cells are particularly efficient in inducing IgE synthesis because they secrete high levels of EL-4, EL-5 and EL-13, which direct lg isotype switching to IgE synthesis

Science 243:14501455 Vaughn JE, Pease DC (1967) Electron microscopy of classically stained astrocytes