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For instance, studies have demonstrated that chronic unpredictable mild stress (CUMS) in rodent models leads to transcriptional changes in key metabolic enzymes, thereby increasing the synthesis of hepatic fatty acids (278).Chronic stress in murine models has been linked to increased hepatic TGs and cholesterol levels, coupled with a decrease in total visceral fat (279)

10.1056/nejmc2004973 [DOI] [PMC free article] [PubMed] [Google Scholar] Vignardi C

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7 The function of certain protein enzymes, as well as some antioxidants, has been enhanced through antioxidant-protein interactions