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Key pharmacokinetic finding: In an 18-subject, single-dose, randomized crossover trial, a single oral dose of S-Acetyl Glutathione produced significantly higher rate (Cmax) and extent (AUCt) of plasma GSH absorption compared to an equivalent dose of standard oral L-Glutathione, with a median Tmax of 1.5 hours for both formulations

However, the causes of B12 deficiency in other population groups must be sought in other contexts, as they do consume this vitamin regularly through their diet, but something is wrong (they do not absorb it well, they do not have the necessary binding proteins, they have a pathology or infection that affects it, they do not produce enough hydrochloric acid, etc.)

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