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Mortality outcomes were determined by correlating participants' data with the National Death Index records through 31 December 2019

For example, MEK inhibition leads to strong overrepresentation of ERK1/2 motif as expected, GSK3 inhibition down-regulates sites that conform to the known GSK3 motif, and mTOR inhibition down-regulated sites with the known mTOR substrate motif as well as substrate sites of its main downstream kinase p70S6K

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*Correspondence: Jie Wang, [email protected] These authors have contributed equally to this work This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Stacked with choline and inositol for enhanced synergistic effects, this supplement ensures you get the essential nutrients needed for overall cell health and performance