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Researchers have found that the lung microbiome profoundly impacts the tumorigenesis, progression, and prognosis of lung cancer

Keap1 has a suppressing role on Nrf2 [86], and it is the key negative regulator of Nrf2 [87]

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By enhancing endogenous antioxidative capacity, such interventions may counteract the aberrant neuroplasticity and protein aggregation underlying tinnitus and neurodegenerative diseases (Scuto et al., 2020

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326,327 This not only prevents the phosphorylation of JNK but also promotes the phosphorylation of STAT3, aiding the shift of macrophages to an anti-inflammatory M2 phenotype