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PLoS One 9, e106338

Lysosomal dysfunction in proteinopathic neurodegenerative disorders: possible therapeutic roles of cAMP and zinc

developed a model of Ox-LDL-induced ferroptosis in HUVECs, showing that CTRP13 intervention increased antioxidant enzyme expression, preventing AS and protecting endothelial cells from ferroptosis ( / mice by reducing mitochondrial damage, boosting glutathione and superoxide dismutase levels, and decreasing LPO and MDA levels

For example, a laminin-mimicking polypeptide (BP-KLVFFKGGDGR-YIGSR) can bind integrin and laminin receptors within tumors and inhibit lung metastasis in melanoma and breast cancer models (222)