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These structures wrap around mitochondrial constriction sites, which are often premarked by endoplasmic reticulum (ER) contact

None of the treatments is recommended by the AAO, generally because of a lack of evidence of their effectiveness rather than substantial evidence of risks

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However, glucose and/or adenosine triphosphate (ATP) deprivation, oxidative stress and compromised mitochondrial function may result in the accumulation of cytotoxic mediators and energy depletion

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Emojevwe V et al (2022) Therapeutic efficacy of N-acetylcysteine and zinc sulphate against di-(2-ethylhexyl) phthalate-induced testicular oxido-nitrergic stress in male Wistar rat