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Clinical studies have shown that the beneficial therapeutic effects of methylprednisolone and glatiramer acetate on MS may be mediated by elevated UA levels [163, 164]

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2021;8(3):rbab012

Because cannabinoid receptor 1 (CB1) activation results in inhibition of selective adenylate cyclase activity, THC binding to CB1 receptors may affect perception, memory, and movement, and may trigger depression

[80] FosB plays a crucial role in the development of drug addictions, since its overexpression in D1-type medium spiny neurons in the nucleus accumbens is necessary and sufficient [note 6] for most of the behavioral and neural adaptations that arise from addiction

A., Wiest M