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Identifying novel interacting proteins with GST pull-downs

In light of the shortage of drug targets, alternative mechanisms such as targeting protein degradation (TPD) and modulating biomolecular condensates offer promising opportunities for the development of first-in-class antiviral drugs

[1] Additionally, the authors indicate that there is still a requirement for successful human trials to be completed prior to clinical translation as there are important differences between rodent and human physiology that could have a significant impact on the efficacy and safety of any agent

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Moreover, in a validation study to confirm the reproducibility of our findings, the glutathione level was reduced in NTG and POAG patients compared with a cataract control group