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When combined with semaglutide, cagrilintide showed enhanced weight loss and improved glycaemic control in individuals with type 2 diabetes 2

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Together, these findings demonstrate: (i) modulatory effects of CD38 mAbs on ADPR-Cyclase and cADPR-Hydrolase activities in the LP-1 line, and (ii) antibody-specific differences in regulating CD38 catalytic functions