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Besides its use as a local and topical anesthetic agent, lidocaine is used to treat ventricular arrhythmias, principally ventricular tachycardia and ventricular premature complexes in all species

The research on this is robust and consistent across multiple autoimmune conditions

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Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizing enzyme system

& Lim, J

Tirzepatide's GLP-1 activation slows heart rate while phentermine's sympathomimetic action increases it, potentially causing palpitations or arrhythmias