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Activation of the p62-Keap1-NRF2 pathway protects against Ferroptosis in hepatocellular carcinoma cells

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In the IL-10-deficient CD mouse model, autophagy is amplified through suppressing the PI3K/Akt/mTOR axis [25, 26], while activation of this pathway attenuated CD symptoms in IL-10 knockout mice[27]

For those in high-performance settings such as long-haul drivers or military personnel, 200 mg of caffeine improved vigilance and task efficiency[12 Trusted Source 2016 - Neuroscience & Biobehavioral Reviews A review of caffeines effects on cognitive, physical and occupational performance ]