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Subsequent MVDA of temporal exometabolite profiles identified the exponential growth phase as the primary window of divergence, allowing us to interrogate metabolic rewiring via an FBA-xAI approach

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This area of TB-500 research remains active, with the nasal spray use format relevant for longitudinal studies examining systemic peptide uptake

Correlation of plasma metabolites with glucose and lipid fluxes in human insulin resistance

Therefore, melatonin can inhibit the growth of breast cancer cells in the MCF-7 and MDA-MB-231 cell lines by inducing cell death by increasing the expression of the apoptotic markers TUNEL and Bax and the autophagy Beclin-1, LC3, and p62 [37]

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