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Various core-shell composite nanocarrier systems not only involve inorganic nanoparticles as cores with biologically compatible materials as coatings but also include structures where drugs are encapsulated with organic materials as core and then coated with inorganic materials

With the possibility of lactate to regulate NAD + metabolism-associated enzymes epigenetically, further studies might be required to elucidate this complex biology

However, there remains a lack of convincing evidence supporting its efficacy [177]

doi: 10.2174/156720211798120990 595 EntezariMFlavarjaniZKRamezaniANikkhahHKarimiSMoghadamHFet al

Similarly, in prostate cancer (22Rv1 and PC-3) cells, apigenin treatment is shown to induce cell cycle arrest at the G0/G1 phase in a dose-dependent manner [78]