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In this case, the mutation is likely to result in higher expression of the neighboring genes and enhanced BDO degradation via oxidation by the encoded dehydrogenases

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Furthermore, mortality was found to be increased in a European population of relatively low selenium status (plasma selenium 89 g/l) on long-term supplementation with 300 g/d (as selenium-yeast) ( Reference Rayman, Winther and Pastor-Barriuso 111 )

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