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Phytother Res Int J Devot Pharmacol Toxicol Eval Nat Prod Deriv 23(5):677686 Huang Y-C et al (2005) A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration

[1] According to the researchers TGF-beta1 induction of angiogenesis requires a rapid and transient apoptotic effect mediated by VEGF/VEGFR2. AHK-Cu, by enhancing levels of the Vascular Endothelial Growth Factor, may possibly activate fibroblasts and endothelial cells