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Nanocarrier technology The development of nanoparticles or liposomes targeting adipocytes can significantly increase the subcutaneous retention time and bioavailability of L-carnitine.For example, PLGA nanoparticles can extend the drug release cycle to 72 hours and reduce the frequency of drug administration

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31,36,45 Several works, describing different neuropathic pain models, confirmed the antinociceptive effect of ALC

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doi:10.1210/jc.20161257CrossRefGoogle ScholarPubMed Cherix, A., Larrieu, T., Grosse, J., Rodrigues, J., McEwen, B., Nasca, C., Sandi, C