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Although the relationship between folic acid intake and the risk of breast cancer is still controversial, a recent meta-analysis, analyzing 23 prospective studies, found that an increment of folate intake decreased the risk of ER-, ER-/PR-, premenopausal breast cancer and had the preventive effects against breast cancer in individuals with alcohol consumption (52)

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According to the CDC, excessive alcohol intake leads to an economic cost of $249 billion per year 15 , with most of the cost (72%) resulting from decreased productivity in the workplace, and 11% of the cost dedicated to health care expenses related to excessive drinking 16

Furthermore, T cells from Bcatc -/- mice display higher rates of glycolysis ( Serine Metabolism Serine is used in proliferating cells for protein synthesis as well as the synthesis of other amino acids, such as glycine and cysteine ( Upon T cell activation, upregulated enzymes of the serine, glycine, one-carbon (SGOC) metabolic network, increase processing of serine into one-carbon metabolism

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