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Bioorganic & Medicinal Chemistry Letters, 2015

Decreased GSH levels and impaired GSH synthesis and recycling have been observed in aging, suggesting a potential therapeutic target for restoring redox balance and mitigating oxidative damage

We explore the multifaceted impacts of these dietary interventions, encompassing their immunomodulatory effects, other biological impacts, and underlying molecular mechanisms

lncRNA H19 can act as a competitive endogenous RNA to bind to miR-19b-3p, thereby enhancing the transcriptional activity of its endogenous target ferritin heavy chain 1(FTH1), and CUL plays a role in promoting ferroptosis by down-regulating lncRNA H19 in lung cancer cells [211]

Because it raises IGF-1, patients should also have periodic checks for malignancy risk factors (as any GH therapy might slightly increase certain cancer risks over the long term)

12 , e1006133 (2016)