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Daily intake of a wide variety of phytochemicals has been shown to possess chemopreventive properties (358) Chemoprevention of cancer involves the inhibition of carcinogenesis by the administration of synthetic and natural agents, and these chemopreventive agents can be broadly grouped into three groups (126)

So this review aimed to summarize the anticancer capacities and the antitumor mechanism of CHE

Integrating multi-omics data and utilizing artificial intelligence can provide deeper mechanistic insights and facilitate personalized approaches by identifying individual variations and optimizing treatment strategies

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however, it is difficult to assume that this mutation has no impact on internalization since no quantitative evaluation was made

Adjusting protocols for specific goals While the standard protocol serves most users well, specific goals may benefit from adjusted approaches