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Because phosphatidylcholine is required in the synthesis of very-low-density lipoprotein (VLDL) particles (see Function), choline deficiency results in impaired VLDL secretion and accumulation of fat in the liver (steatosis), ultimately leading to liver damage

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One important application of the molecular network is in drug repurposing

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This variability underscores the urgent need for standardized protocols and quality control measures, including robust characterization techniques such as nanoparticle tracking analysis, electron microscopy, flow cytometry, and proteomic profiling [141]

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