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T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays

Tesofensine carries CNS-related side effects consistent with monoamine reuptake inhibition: insomnia (reported in 18% of participants), dry mouth (32%), constipation (17%), and dose-dependent increases in heart rate and blood pressure

Further investigations have identified two broad categories of organ failure in AP: early primary organ failure, which occurs within 72 h due to systemic inflammation, and late secondary organ failure, which typically develops after one week and is often linked to infectious pancreatic necrosis

Arginine is required for surface expression of the CD3 chain [235, 236]

doi: 10.1021/jf020444+ 148