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Although several small bowel preparation methods have been reported, no well-designed prospective controlled studies directly comparing these methods have been performed

No detectable local or systemic toxicity was observed after repeated administration

doi: 10.1038/s41420-020-0285-0 144 WangFSunHZuoBShiKZhangXZhangCet al

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First, enhanced bioavailability: nanocarriers (e.g., liposomes and polymeric nanoparticles) improve solubility and stability of poorly water-soluble drugs like OXY and colchicine, ensuring consistent therapeutic plasma levels (Peng et al., 2023

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