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One of the earliest symptoms of vitamin C deficiency is fatigue, thought to be related to decreased synthesis of L-carnitine (41)

Whether amino acid stimulation of the developing immune cells could modulate the CNS innate immune system via immune-microglia interactions should be further studied

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Nascas animal studies suggest that acetyl-L-carnitine, a crucial mediator of fat metabolism and energy production throughout the body, plays a special role in the brain, where it works at least in part by preventing the excessive firing of excitatory nerve cells in brain regions called the hippocampus and frontal cortex

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The occurrence of this complaint comes up readily on internet search engines by entering such words as body odour, and there are patient advocacy groups in some developed countries