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In the 1980s, the Slavic researchers whom we have to thank for the bulk of our knowledge about short peptides were focused on the possibilities of a thymic peptide bioregulator called thymalin which they found could spur the thymus to re-grow, thus enhancing immune function

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According to published studies, cell therapy still faces significant challenges in terms oflong-term safety, treatment durability, cell preparation and cost, individual variability, and delivery methods [149]

77737 Mischoulon, D., & Fava, M

Overall, although rapid progress has been achieved in this field in recent years, some crucial issues and challenges remain to be solved

TAMs are the most abundant immune cells in the TME, accounting for about 50% of the tumor mass [137, 138]