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One aspect of the invention pertains to the administration of one or more NNMT inhibitors by, for example, contacting one or more cells of an animal to: (a) treat and/or prevent muscular disorders, including, but not limited to, sarcopenia, muscle atrophy, Duchenne muscular dystrophy, Becker muscular dystrophy, Limb-girdle muscular dystrophies, Pompe disease, cardiac myopathies, pulmonary disorders

Expired folic acid supplements may not deliver enough folate to the parent and the developing fetus

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B12 supplementation does not enhance metabolic rate or promote fat loss in people with normal B12 status

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