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Additionally, three of the six variants exhibited greater sensitivity than the parental p53-null OVCAR5 cells, including the positive control R175H (Fig

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The preference for novel object% and discrimination ratio was calculated according to the following formula: Euthanasia and sampling After the behavioral tests, all rats were euthanized by cervical dislocation, and the brain was excised rapidly and washed with cold saline to remove any blood clots